Get ready for an electrifying 2025 season as the Arizona Cardinals unveil their highly anticipated schedule. The Cardinals, led by their dynamic quarterback Kyler Murray, aim to build upon their impressive performance last year and make a deep playoff run this season. With a formidable lineup of opponents, including divisional rivals and top contenders, every game promises to be a thrilling battle. Mark your calendars and prepare to witness the Cardinals soar to new heights in 2025.
The Cardinals will kick off their season with a home game against the NFC West rival San Francisco 49ers. This matchup is sure to set the tone for the season, as both teams are known for their high-octane offenses and fierce defenses. Murray will face off against 49ers quarterback Trey Lance in a battle of young stars. In Week 2, the Cardinals will travel to face the New York Giants, a team that has been quietly improving over the past few seasons. The Giants’ strong defense will pose a significant challenge for the Cardinals’ offense.
The Cardinals’ toughest stretch of the season comes in Weeks 5 through 9, when they face a gauntlet of top contenders. In Week 5, they travel to face the defending NFC champion Philadelphia Eagles. The Eagles’ formidable defense, led by Nick Sirianni, will be a major test for Murray and the Cardinals’ offense. In Week 6, the Cardinals return home to face the Kansas City Chiefs, one of the most dominant teams in the NFL. Patrick Mahomes and the Chiefs’ high-powered offense will be a formidable challenge for the Cardinals’ defense.
Arizona Cardinals 2025 Preseason Slate Released
The Arizona Cardinals have released their 2025 preseason schedule, which features three home games and one road contest. The Cardinals will open their preseason at home against the Kansas City Chiefs on August 15th, followed by a road game against the Los Angeles Rams on August 22nd. They will then return home to face the New Orleans Saints on August 29th, before wrapping up their preseason with a home game against the Dallas Cowboys on September 3rd.
Arizona Cardinals 2025 Preseason Schedule
| Date | Opponent | Location |
|---|---|---|
| August 15 | Kansas City Chiefs | State Farm Stadium |
| August 22 | Los Angeles Rams | SoFi Stadium |
| August 29 | New Orleans Saints | State Farm Stadium |
| September 3 | Dallas Cowboys | State Farm Stadium |
Regular Season Matchups for the 2025 Cardinals
The Arizona Cardinals will face a challenging schedule in 2025, with games against some of the league’s top teams. The Cardinals will open the season at home against the San Francisco 49ers, a team they beat in the playoffs in 2023. They will then travel to face the New York Giants, who won the NFC East in 2023. The Cardinals’ first home game against a division rival will be in Week 3, when they host the Los Angeles Rams.
Notable Matchups
The Cardinals will have several notable matchups in 2025, including:
- Week 1: at San Francisco 49ers
- Week 2: at New York Giants
- Week 3: vs. Los Angeles Rams
- Week 4: at Seattle Seahawks
- Week 5: vs. Denver Broncos
- Week 6: at New England Patriots
- Week 7: vs. Chicago Bears
- Week 8: at Dallas Cowboys
- Week 9: vs. Tampa Bay Buccaneers
- Week 10: BYE
- Week 11: at Minnesota Vikings
- Week 12: vs. Carolina Panthers
- Week 13: at Los Angeles Rams
- Week 14: vs. Seattle Seahawks
- Week 15: at Houston Texans
- Week 16: vs. Green Bay Packers
- Week 17: at Kansas City Chiefs
- Week 18: vs. San Francisco 49ers
The Cardinals will also play two games against each of their NFC West rivals: the 49ers, Seahawks, and Rams. The Cardinals will face the 49ers in Weeks 1 and 18, the Seahawks in Weeks 4 and 14, and the Rams in Weeks 3 and 13.
| Week | Opponent | Home/Away |
|---|---|---|
| 1 | San Francisco 49ers | Away |
| 2 | New York Giants | Away |
| 3 | Los Angeles Rams | Home |
Key Home Games on the Cardinals’ 2025 Schedule
The Arizona Cardinals will play 16 games at State Farm Stadium during the 2025 season. Eight of those games will be against NFC West opponents, including the Seattle Seahawks, San Francisco 49ers, and Los Angeles Rams. The Cardinals will also host the Dallas Cowboys, New York Giants, and New Orleans Saints in non-divisional home games.
Must-See Matchups at State Farm Stadium
The Cardinals’ home schedule features several marquee matchups against some of the NFL’s top teams. Here are three must-see games that Cardinals fans won’t want to miss:
– Week 4: Dallas Cowboys
The Cowboys are one of the NFL’s most storied franchises, and their visit to State Farm Stadium will be a highly anticipated event. Dallas boasts a high-powered offense led by quarterback Dak Prescott and running back Ezekiel Elliott. The Cardinals’ defense will need to be at its best to slow down the Cowboys’ potent attack.
– Week 6: San Francisco 49ers
The 49ers have been one of the NFL’s most dominant teams in recent years, and their matchup against the Cardinals will be a battle between two NFC West rivals. San Francisco’s defense is one of the league’s best, and the Cardinals will need to find a way to move the ball against them.
– Week 11: New York Giants
The Giants are a rising team under head coach Brian Daboll, and their visit to State Farm Stadium will be a good test for the Cardinals. New York has a young and talented roster, and they could be a playoff contender in 2025. The Cardinals will need to be at their best to defeat the Giants and continue their push for a division title.
Arizona’s Challenging Away Schedule in 2025
The Arizona Cardinals will face a challenging away schedule in 2025, with road trips to some of the NFL’s toughest venues.
Atlanta Falcons
The Cardinals will open the 2025 season on the road against the Atlanta Falcons. The Falcons have been a tough opponent for the Cardinals in recent years, winning three of the last four meetings between the two teams.
Baltimore Ravens
The Cardinals will also travel to Baltimore to face the Ravens in 2025. The Ravens are one of the most physical teams in the NFL, and they have a strong home-field advantage at M&T Bank Stadium.
### Cleveland Browns
The Browns have been one of the most improved teams in the NFL in recent years, and they will be a tough test for the Cardinals in 2025. The Browns have a strong defense and a talented offense led by quarterback Deshaun Watson.
Green Bay Packers
The Cardinals will travel to Green Bay to face the Packers in 2025. The Packers are one of the most storied franchises in NFL history, and they have a passionate fan base that makes Lambeau Field one of the toughest places to play in the NFL.
| Week | Opponent | Location | Date |
|---|---|---|---|
| 1 | Atlanta Falcons | Atlanta | September 14, 2025 |
| 2 | Baltimore Ravens | Baltimore | September 21, 2025 |
| 3 | Cleveland Browns | Cleveland | September 28, 2025 |
| 4 | Green Bay Packers | Green Bay | October 5, 2025 |
NFC West Division Battles in 2025
Home Games
The Cardinals will host each of their NFC West rivals once in 2025. They’ll face the Rams in Week 12, the 49ers in Week 15, and the Seahawks in Week 16.
Road Games
The Cardinals will travel to each of their NFC West rivals once in 2025. They’ll face the Seahawks in Week 8, the Rams in Week 13, and the 49ers in Week 17.
Key Divisional Matchups
The Cardinals’ most important divisional matchup in 2025 is likely to be their Week 15 contest against the 49ers. The 49ers are one of the most talented teams in the NFC West, and they’ll be looking to avenge their loss to the Cardinals in Week 1 of the 2024 season.
Another key divisional matchup for the Cardinals is likely to be their Week 16 contest against the Seahawks. The Seahawks are a perennial playoff contender, and they’ll be looking to snap their two-game losing streak against the Cardinals in 2025.
NFC West Standings in 2025
The NFC West is one of the toughest divisions in the NFL, and it’s likely to be a close race in 2025. The Cardinals will need to play well in their divisional matchups if they want to win the division and make a run in the playoffs.
Predicted NFC West Standings in 2025
| Team | Wins | Losses | Ties |
|---|---|---|---|
| 49ers | 11 | 5 | 0 |
| Cardinals | 10 | 6 | 0 |
| Rams | 9 | 7 | 0 |
| Seahawks | 6 | 10 | 0 |
High-Profile Primetime Games for the Cardinals in 2025
2025 promises to be an exciting year for Arizona Cardinals fans, with the team slated to play several high-profile primetime games. These games will provide a national stage for the Cardinals to showcase their talent and make a statement to the rest of the NFL.
Week 8: Thursday Night Football vs. Kansas City Chiefs
The Cardinals will host the defending AFC champions, the Kansas City Chiefs, on Thursday Night Football in Week 8. This game is sure to be a clash of offensive titans, with both teams featuring explosive passing attacks. Kyler Murray and Patrick Mahomes are two of the most exciting young quarterbacks in the NFL, and this matchup is sure to deliver plenty of fireworks.
Week 12: Sunday Night Football vs. Green Bay Packers
The Cardinals will travel to Lambeau Field to face the Green Bay Packers on Sunday Night Football in Week 12. This will be a rematch of the classic 2021 divisional playoff game that the Packers won in overtime. The Cardinals will be looking to avenge that loss and prove that they can beat one of the NFC’s elite teams on the road.
Week 13: Monday Night Football vs. Pittsburgh Steelers
The Cardinals will host the Pittsburgh Steelers on Monday Night Football in Week 13. This is a historic matchup between two of the NFL’s most storied franchises. The Steelers are one of the most successful teams in NFL history, and they will be looking to add to their legacy against a young and rising Cardinals team.
Week 15: Saturday Night Football vs. Philadelphia Eagles
The Cardinals will travel to Philadelphia to face the Philadelphia Eagles on Saturday Night Football in Week 15. This game is sure to be a physical battle, as both teams feature strong running games. The Cardinals will need to find a way to slow down Eagles quarterback Jalen Hurts, who is one of the most dynamic players in the NFL.
| Primetime game | Date | Time | Opponent | TV Network |
|---|---|---|---|---|
| Thursday Night Football | Week 8 | 8:20 PM ET | Kansas City Chiefs | Amazon Prime Video |
| Sunday Night Football | Week 12 | 8:20 PM ET | Green Bay Packers | NBC |
| Monday Night Football | Week 13 | 8:15 PM ET | Pittsburgh Steelers | ESPN |
| Saturday Night Football | Week 15 | 8:15 PM ET | Philadelphia Eagles | Fox/NFL Network |
Week 17: Sunday Night Football vs. Los Angeles Rams
The Cardinals will close out the regular season by hosting the Los Angeles Rams on Sunday Night Football in Week 17. This is a crucial game for both teams, as they will be vying for a playoff spot. The Cardinals will need to win this game to secure their place in the postseason.
Cardinals’ Bye Week in 2025 and Surrounding Fixtures
Bye Week
The Cardinals will have their bye week in 2025 during Week 10, which falls between their games against the Carolina Panthers and the San Francisco 49ers. This will give the team some much-needed rest and time to prepare for the second half of the season.
Surrounding Fixtures: Week 9-11
| Week | Opponent | Location | Date |
|---|---|---|---|
| 9 | Philadelphia Eagles | State Farm Stadium | November 2, 2025 |
| 10 | BYE | – | – |
| 11 | San Francisco 49ers | Levi’s Stadium | November 16, 2025 |
Week 9: Philadelphia Eagles
The Cardinals will face the Philadelphia Eagles in Week 9 at State Farm Stadium. The Eagles are a tough opponent, but the Cardinals will be looking to avenge their 2024 loss to Philadelphia.
Week 11: San Francisco 49ers
The Cardinals will travel to Levi’s Stadium in Week 11 to take on the San Francisco 49ers. The 49ers are one of the most talented teams in the NFL, so the Cardinals will need to be at their best to come away with a victory.
8. Potential Playoff Matchups Based on the 2025 Schedule
AFC Round One
The Cardinals are projected to finish the 2025 regular season with a record of 10-7, which would give them the No. 6 seed in the NFC. This would set up a potential matchup with the No. 3 seed in the AFC, which is currently projected to be the Cincinnati Bengals.
NFC Divisional Round
If the Cardinals win their Wild Card matchup, they would then face the No. 2 seed in the NFC, which is currently projected to be the San Francisco 49ers. This would be a rematch of the 2020 NFC Championship Game, which the Cardinals lost 20-17.
NFC Championship Game
If the Cardinals win their Divisional Round matchup, they would then face the No. 1 seed in the NFC, which is currently projected to be the Philadelphia Eagles. The Eagles have been one of the most dominant teams in the NFL over the past two seasons, so this would be a tough matchup for the Cardinals.
Super Bowl LIX
If the Cardinals win the NFC Championship Game, they would then represent the NFC in Super Bowl LIX, which will be played in New Orleans, Louisiana. The Cardinals would face the winner of the AFC Championship Game, which is currently projected to be the Buffalo Bills.
| Round | Opponent | Location |
|---|---|---|
| Wild Card | Cincinnati Bengals | Paul Brown Stadium, Cincinnati, Ohio |
| Divisional Round | San Francisco 49ers | Levi’s Stadium, Santa Clara, California |
| NFC Championship Game | Philadelphia Eagles | Lincoln Financial Field, Philadelphia, Pennsylvania |
| Super Bowl LIX | Buffalo Bills | Mercedes-Benz Superdome, New Orleans, Louisiana |
Fantasy Football Implications of the Cardinals’ 2025 Schedule
Week 1: at San Francisco 49ers
The Cardinals open the season with a difficult road matchup against a talented 49ers defense. Kyler Murray should be able to put up decent numbers, but the Cardinals’ running backs could struggle against a tough 49ers front seven.
Week 2: Kansas City Chiefs
The Chiefs are always a high-scoring offense, so Murray and the Cardinals’ passing attack will have plenty of opportunities to put up points. However, the Cardinals’ defense will need to be at their best to slow down Patrick Mahomes and company.
Week 3: at Baltimore Ravens
The Ravens have a strong defense, but their offense is not as potent as it once was. Murray could have a big game in this one, but the Cardinals’ running backs will need to step up to keep the Ravens’ defense honest.
Week 4: Carolina Panthers
The Panthers are a rebuilding team, so this should be a good opportunity for the Cardinals to get a win. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Panthers defense.
Week 5: at Denver Broncos
The Broncos are a tough team, but the Cardinals should be able to win this game if they can protect Murray and keep their running backs healthy. Murray should be able to put up solid numbers, but the Cardinals’ running backs could struggle against a strong Broncos front seven.
Week 6: Seattle Seahawks
The Seahawks are always a tough opponent, but the Cardinals should be able to win this game if they can control the tempo of the game and keep Russell Wilson from getting into a rhythm. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Seahawks defense.
Week 7: at Washington Commanders
The Commanders are a rebuilding team, so this should be a good opportunity for the Cardinals to get a win. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Commanders defense.
Week 8: Minnesota Vikings
The Vikings are a tough team, but the Cardinals should be able to win this game if they can protect Murray and keep their running backs healthy. Murray should be able to put up solid numbers, but the Cardinals’ running backs could struggle against a strong Vikings front seven.
Week 9: BYE
The Cardinals have a bye in Week 9.
Week 10: Philadelphia Eagles
The Eagles are a tough team, but the Cardinals should be able to win this game if they can control the tempo of the game and keep Jalen Hurts from getting into a rhythm. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Eagles defense.
Week 11: at Los Angeles Chargers
The Chargers are a tough team, but the Cardinals should be able to win this game if they can protect Murray and keep their running backs healthy. Murray should be able to put up solid numbers, but the Cardinals’ running backs could struggle against a strong Chargers front seven.
Week 12: Las Vegas Raiders
The Raiders are a rebuilding team, so this should be a good opportunity for the Cardinals to get a win. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Raiders defense.
Week 13: at New York Giants
The Giants are a tough team, but the Cardinals should be able to win this game if they can control the tempo of the game and keep Daniel Jones from getting into a rhythm. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Giants defense.
Week 14: San Francisco 49ers
The 49ers are a tough team, but the Cardinals should be able to win this game if they can protect Murray and keep their running backs healthy. Murray should be able to put up solid numbers, but the Cardinals’ running backs could struggle against a strong 49ers front seven.
Week 15: at Tennessee Titans
The Titans are a tough team, but the Cardinals should be able to win this game if they can control the tempo of the game and keep Derrick Henry from getting into a rhythm. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Titans defense.
Week 16: Atlanta Falcons
The Falcons are a rebuilding team, so this should be a good opportunity for the Cardinals to get a win. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Falcons defense.
Week 17: at Los Angeles Rams
The Rams are a tough team, but the Cardinals should be able to win this game if they can protect Murray and keep their running backs healthy. Murray should be able to put up solid numbers, but the Cardinals’ running backs could struggle against a strong Rams front seven.
Week 18: at Seattle Seahawks
The Seahawks are always a tough opponent, but the Cardinals should be able to win this game if they can control the tempo of the game and keep Russell Wilson from getting into a rhythm. Murray should be able to put up big numbers in this one, and the Cardinals’ running backs should also find success against a weak Seahawks defense.
Impact of the 2025 Schedule on the Cardinals’ Projected Success
The Arizona Cardinals’ 2025 schedule presents both opportunities and challenges for the team’s projected success.
Strength of Schedule
The Cardinals’ strength of schedule is expected to be relatively difficult, with opponents having a combined winning percentage of .525 in 2024.
Home Field Advantage
The Cardinals will play seven home games and nine away games in 2025. Having the home-field advantage in a majority of their games could be a significant advantage.
Divisional Games
The Cardinals will face each of their divisional rivals twice, with one home game and one away game against each. These matchups will be crucial in determining the team’s standing within the NFC West.
Key Non-Divisional Games
The Cardinals have some tough non-divisional games scheduled, including a matchup against the reigning Super Bowl champion Kansas City Chiefs. These games will test the team’s ability to compete against elite opponents.
Stretch Run
The Cardinals’ final four games of the season are against NFC opponents, with two of those games being against divisional rivals. This stretch will be critical in determining the team’s playoff chances.
10. Bye Week Timing
The Cardinals’ bye week comes in Week 9. This gives the team a chance to rest and regroup before a challenging final stretch of the season.
| Week | Opponent | Location |
|---|---|---|
| 1 | Detroit Lions | Home |
| 2 | Tennessee Titans | Away |
| 3 | Jacksonville Jaguars | Home |
| 4 | Seattle Seahawks | Away |
| 5 | Tampa Bay Buccaneers | Home |
| 6 | BYE | – |
| 7 | Dallas Cowboys | Away |
| 8 | Baltimore Ravens | Home |
| 9 | Los Angeles Rams | Away |
| 10 | Buffalo Bills | Home |
| 11 | New York Giants | Away |
| 12 | San Francisco 49ers | Home |
| 13 | New Orleans Saints | Away |
| 14 | Las Vegas Raiders | Home |
| 15 | Minnesota Vikings | Away |
| 16 | Seattle Seahawks | Home |
| 17 | Philadelphia Eagles | Away |
Arizona Cardinals 2025 NFL Schedule: A Comprehensive Look at the Upcoming Season
The Arizona Cardinals have released their 2025 NFL schedule, which features an exciting mix of home and away games against some of the league’s top teams. The Cardinals will open their season at home against the reigning Super Bowl champions, the New England Patriots, in a highly anticipated matchup. They will then face a tough road test in Week 2 against the San Francisco 49ers, who have emerged as a powerhouse in the NFC West. The Cardinals will have a chance to avenge their Week 1 loss when they host the Patriots in Week 10.
The Cardinals’ 2025 schedule also includes several key matchups against division rivals. They will face the Seattle Seahawks twice, once at home and once on the road, and will also play the Los Angeles Rams and the San Francisco 49ers twice. The Cardinals will also host the Green Bay Packers, who have been a consistent playoff contender in recent years, and will travel to face the Baltimore Ravens, who have one of the most dynamic offenses in the NFL. The Cardinals will close out their 2025 season at home against the Kansas City Chiefs, who have established themselves as one of the league’s elite teams under the leadership of quarterback Patrick Mahomes.
Overall, the Cardinals’ 2025 NFL schedule presents a challenging but exciting opportunity for the team to prove itself against some of the league’s best. With a talented roster and a supportive home crowd, the Cardinals will be looking to make a deep playoff run in 2025.
People Also Ask About Arizona Cardinals Schedule 2025
When is the Cardinals’ first home game in 2025?
The Cardinals’ first home game in 2025 is in Week 1 against the New England Patriots.
Who do the Cardinals face in Week 2 of the 2025 season?
The Cardinals face the San Francisco 49ers in Week 2 of the 2025 season.
How many times do the Cardinals play the Seahawks in 2025?
The Cardinals play the Seahawks twice in 2025, once at home and once on the road.
Who is the Cardinals’ toughest opponent in 2025?
The Cardinals’ toughest opponent in 2025 is likely the Kansas City Chiefs, who have been a consistent playoff contender in recent years.
When is the Cardinals’ last regular season game in 2025?
The Cardinals’ last regular season game in 2025 is at home against the Kansas City Chiefs.
